Cognitive Longevity & Dementia Prevention

Our services are designed for adults who:

• Have a family history of Alzheimer's disease or dementia.

• Are concerned about memory changes, brain fog, or declining mental clarity.

• Have subjective cognitive impairment (SCI), mild cognitive impairment (MCI) or early cognitive changes.

• Want to understand their personal genetic and metabolic risk factors.

• Have cardiovascular or metabolic conditions associated with cognitive decline.

• Want to take a proactive approach to healthy aging, cognitive longevity and dementia prevention.

Who Can Benefit From Cognitive Longevity Care?

Your brain health is not entirely determined by your age or genetics. Research shows that many factors associated with cognitive decline and dementia risk are potentially modifiable.

The 2024 Lancet Commission on dementia prevention, intervention, and care—an international collaboration of leading experts—estimated that addressing 14 potentially modifiable risk factors across the lifespan could prevent or delay nearly 45% of dementia cases.

This landmark report reflects a much broader and growing body of research demonstrating that lifestyle, cardiovascular and metabolic health, environmental exposures, and other modifiable factors can influence cognitive health.

At Marathon Wellness, we use this evolving science to help individuals better understand their personal risk factors and develop a proactive, individualized strategy for cognitive longevity and dementia risk reduction.

A Personalized Approach to Dementia Risk Reduction

• Advanced metabolic testing: Insulin resistance, glucose regulation, lipid health, inflammation, methylation status, consideration of gut health, hormonal balance, and other cardiometabolic markers.

• Nutritional assessment: Vitamin B12, B6, vitamin D, folate, zinc, magnesium, copper, iron status, nutritional lithium, omega-3, and other micronutrients when clinically indicated.

• Genetic risk assessment: APOE testing and selected genomic insights, with appropriate counseling.

• Cognitive assessment: Baseline cognitive screening and longitudinal monitoring when appropriate.

• Alzheimer's disease biomarkers: Consideration of emerging blood-based biomarkers when clinically appropriate, alongside conventional diagnostic evaluation.

• Lifestyle and environmental assessment: Sleep quality, physical activity, stress, nutrition, medication effects, and other potentially modifiable influences.

Testing is individualized according to your history, goals, clinical needs, and budget.

Our evaluations may include:

Cognitive health is influenced by the interaction of genetics, metabolism, vascular health, nutrition, sleep, physical activity, environmental and lifestyle factors.

Rather than focusing on a single risk factor, our approach considers the whole person.

Why Choose Marathon Wellness? Personalized Integrative Brain Health Strategies

Explore a Proactive Approach to Your Brain Health

Whether you are concerned about your family history, experiencing early memory changes, or simply want to protect your cognitive health as you age, Marathon Wellness can help you develop an individualized plan. Led by Rachel Kermen, MD, Marathon Wellness brings together expertise in brain health, neurorehabilitation, integrative medicine, and lifestyle medicine.

Our virtual practice offers extended physician consultations, individualized laboratory assessments, and comprehensive membership programs supported by a functional medicine nutritionist and health coach.

We focus on helping patients translate complex medical information into practical, sustainable strategies.

Dementia risk reduction is not a guarantee of prevention. Cognitive testing and biomarker evaluation are individualized, and our care complements rather than replaces primary care, conventional neurologic assessment and treatment

Based on your clinical history, testing, and goals, our team develops a personalized care plan with the following:

• Team-based support with nutritionist and health coaching care

• Metabolic and cardiovascular risk reduction

• Stress-management techniques and mind-body practices

• Cognitive stimulation strategies

• Targeted high-quality supplementation when clinically appropriate

• Longitudinal monitoring of symptoms and relevant health measures.

• Monitoring cognitive performance and changes in relevant health biomarkers.

For selected patients, specialized nutritional approaches, including ketogenic metabolic therapy, may be discussed when appropriate, with attention to the current evidence and necessary clinical supervision